Showing posts with label animal testing. Show all posts
Showing posts with label animal testing. Show all posts

Monday, July 20, 2015

#AnimalTesting is becoming too #severe to turn a #BlindEye to. - http://clapway.com/2015/07/20/new-revealing-figures-shed-light-on-animal-testing-in-ireland-225/

IRELAND: The Health Products Regulatory Authority (HPRA) has inadvertently shed some light on the nature of animal testing recently, with their annual report logging 225,000 cases in the last year alone. Responsible for for facilitating between the suppliers of these animals and the laboratories they wind up in, as well as the maintaining and inspecting of the practices taken within these labs, the HPRA is coming under fire from animal rights activists worldwide, disgusted by the results shown in their report.shed some light on the issue of animal testing recently, with their latest figures reporting over 225,000 cases of testing in the last year alone.


KINDS OF ANIMALS TESTED


According to the HPRA’s report, over 200,000 of these cases involved the use of mice, making up 90% of the total. Most of the tests done on mice—as well as other rodents, including 10,456 rats, 2,107 guinea pigs, and 1,539 rabbits—were cases are categorized as “regulatory and other routine production—” a requirement under EU law to research the toxicity and general safety of human pharmaceutical drugs.


Of these numbers, 90,000 mice, 1,104 rats and 36 rabbits were reported as having undergone experiments so severe, they became unable to be used again for animal testing.


Thousands of cows, sheep and pigs were also subject to testing, both for pharmaceutical and human cancer research. Figures also show over 1,200 cases of cats and dogs being subject to animal testing, however, they were limited only to veterinary-related medications and procedures. Other animals subjected to testing include horses, domestic fowl, ferrets, and fish.


WHAT’S BEING DONE ABOUT IT


According to the HPRA, there isn’t much we can do about it right now, as there are currently no possible alternatives to test for biological responses to drugs and medical procedures. They are insistent that the EU animal rights laws currently in place holds its own as among the most advanced legislation in the world, made with the goal to ensure the test subjects receive as much care and general well-being as they need.


The legislation currently active claims to reduce the total amount of tests done, seek alternatives to animal testing whenever possible, and fine-tune the methods already used in order to make them more humane.


However, animal rights activists such as John Carmody, representative and spokesman for the Animal Rights Action Network aren’t buying it, finding the new figures “shocking, even to the hardest of hearts.”


ARAN is one of many animal rights organizations pushing for deeper scrutiny into how research is conducted through animal testing, calling for more transparency and stricter laws to prevent the suffering of animals in laboratories across the globe.


The legislation currently active claims to reduce the total amount of tests done, seek alternatives to animal testing whenever possible, and fine-tune the methods already used in order to make them more humane.


Animal rights activists, sick of the same empty promises from the HPRA made year after year with no real results still aren’t buying it. John Carmody, representative and spokesman for the Animal Rights Action Network finds the new figures “shocking, even to the hardest of hearts,” seeking further change and progress than the HPRA has been able to deliver. ARAN is one of many animal rights organizations pushing for deeper scrutiny into how research is conducted through animal testing, calling for more transparency and stricter laws to prevent the suffering of animals in laboratories across the globe.



 


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New Revealing Figures Shed Light on Animal Testing in Ireland

Wednesday, June 24, 2015

A win for animal welfare AND medicine.- http://clapway.com/2015/06/24/human-organs-on-chips-could-end-animal-testing-234/

Scientists at the Wyss Institute and Harvard University have created a microchip that mimics human organs.


The Organs-On-Chips could one day replace animal testing because they are designed to mimic the architecture and functions of human organs such as the heart, lungs, and intestines. These chips could be a viable alternative to animal testing which is many times unable to accurately predict how drugs interact with human tissues.


“This is a big win towards achieving our Institute’s mission of transforming medicine and the environment by developing breakthrough technologies and facilitating their translation from the benchtop to the marketplace,” said Wyss Institute Founding Director Don Ingber, M.D., Ph.D., and leader of the Wyss Institute’s Organs-on-Chips team.


THE MICROCHIP COULD END ANIMAL TESTING


Each organ-on-chip is a clear polymer stick which contains hollow micro-channels which are lined with human cells. The scientists at the Wyss Institute plan to link 10 different organs-on-chips together in order to mimic a human organ system. The mini system would provide insights into drug efficacy and safety that has never been possible before.


THE FUTURE OF BIOTECHNOLOGY


According to the Wyss Institute, the chip has many future applications. Besides being a viable alternative to animal testing for pharmaceutical effectiveness, the chip could test the safety of cosmetics, test the toxicity of chemicals, be used to develop vaccines, and be used to combat bio-terrorism threats.


SCIENTISTS WIN A PRESTIGIOUS DESIGN AWARD


The development of the chip was a collaborative effort between Wyss Institute, government entities such as the FDA and NIH, and industrial partnerships. The scientists wanted to collaborate early with corporations that could quickly bring the chip to the marketplace.


London’s Design Museum was so impressed with the invention that they have given the Wyss Institute’s chip the Design of the Year 2015 award.


“This is the epitome of design innovation – elegantly beautiful form, arresting concept and pioneering application,” said Paola Antonelli, design curator at New York’s Museum of Modern Art, who nominated the organs-on-chips for the Design of the Year award.


“The team of scientists that produced this remarkable object don’t come from a conventional design background. But what they have done is clearly a brilliant piece of design,” Deyan Sudjic, director of the London Design Museum.


Image credit: Wyss Institute/Harvard University



 


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Human Organs-on-Chips Could End Animal Testing